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Research News | Drug News | Conference News
Mechanisms and Memory: The Choreography of CREB, the Balance of BDNF
July 16, 2010
Two new papers detail specific, discrete pathways of memory formation that share a common element, namely, signaling by CREB...
Toxic TDP-43 Too Tough to Degrade, Plays Prion
July 16, 2010
TDP-43 is intimately linked with ALS, but the mystery remains as to what the protein is normally meant to do, and what goes wrong when it mutates...
New Mechanism Identified that Muscles Use to Regulate Nerves
July 13, 2010
Researchers at the University of Aberdeen and the University of Otago, New Zealand have recently reported that they have identified a protein produced by muscles that helps motor nerves -- the nerves that tell our muscles to work -- produce a large enough stimulus to actually trigger muscle contraction. Their new findings suggest applying the protein, TGFbeta2, restored lost signal strength to sick motor neurons, at least in the short term. They report these intriguing findings in the Proceedings of the National Academy of Sciences.
Mouse Screen Yields Pro-neurogenesis Elixir
July 9, 2010
Scientists on an optimistic fishing expedition, involving 1,000 small molecules and hundreds of mice, have caught a big one with a chemical that promotes adult neurogenesis...
Going Nuclear: First Function for FUS Mutants
July 8, 2010
Large proteins need a key—in the form of a nuclear localization sequence—to unlock the transporters that let them into the cell's inner sanctum...
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