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ALS Gene Expression and Biomarkers: A Better Way to Microarray
July 4, 2010
Microarrays tantalize investigators with the promise of a new smorgasbord of genes to explore and proteins to target with therapeutics...


Mutant SOD1 Inflames If Not Quenched by Autophagy
July 2, 2010
Misfolded proteins can gum up the cell's works by glomming together and boosting inflammation...


Motor Neuron Disease Risk Factors: Fresh miRNA Clue, KIFAP3 Letdown
June 29, 2010
Sifting through the genome has netted several mutations responsible for motor neuron diseases, but scientists still cannot explain the cause for most incidences...


ENS 2010: SECARS Microscope Technology Brings Potential New Insight Into The Occurrence Of ALS
June 27, 2010
A non-invasive imaging technology called Surface-Enhanced Coherent Anti-Stokes Raman Scattering (SECARS) microscopy is being developed for diagnostic applications for ALS. In a study presented at the Meeting of the European Neurological Society (ENS 2010) in Berlin, researchers presented their results using this new technology to charactericize disease pathology ALS rats.


Researchers Develop Novel Approach to Identify Disease-Relevant Genes in ALS
June 24, 2010
Researchers led by the Los Angeles Biomedical Research Institute (LA BioMed) have developed a new approach to identifying disease-relevant genes in complex disorders. The new method was applied to ALS, and reported in the recent online volume of the journal Human Molecular Genetics. "By developing new methods to examine disease relevant genes in neurological disorders, we move closer to unlocking the mysteries of ALS and other neurological diseases," said Stanislav L. Karsten, PhD, one of the study's authors. "This study provides us new clues to continue to investigate the causes and to seek the therapies that can make a difference in the lives of those suffering from neurological disorders."






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