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Do Membraneless Organelles Host Fibril Nucleation?
October 8, 2015
Two proteins involved in amyotrophic lateral sclerosis (ALS) precipitate formation of cellular granules by condensing into liquid droplets, according to recent...
Catalog of Humanity—Variation in 2,500 Genomes Ready for Perusal
October 2, 2015
Once upon a time, sequencing a single genome was something to brag about. Those days are gone. In the October 1 Nature, a consortium of researchers publishes its final report on...
Do Sleeper Viruses Awaken in ALS?
October 2, 2015
A hibernating retrovirus, prodded from slumber, can provoke neurodegeneration, according to a paper in the September 30 Science Translational Medicine. Human...
ER Stress Links SMA and ALS
September 28, 2015
Spinal muscular atrophy (SMA), the most common fatal genetic disease of young children, is caused by mutations in the survival of motor neuron 1, telomeric (SMN1) gene. Although...
C9ORF72 RNA Foci Acquitted of Toxic Charge—in Fruit Flies
September 25, 2015
Hexanucleotide repeats in the C9ORF72 gene, which cause both frontotemporal dementia and amyotrophic lateral sclerosis, spew a fusillade of potentially toxic molecules into the...

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