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ALS Gene Repeats Obstruct Traffic Between Nucleus and Cytoplasm
August 28, 2015
Could a molecular traffic jam at the nuclear membrane explain one kind of motor neuron disease? Extensive hexanucleotide repeats in the C9ORF72 gene, which are...
Making Muscles in a Dish Could Pave the Way for New Therapies
August 21, 2015
Understanding the cross-talk between degenerating neurons and their target muscles could aid in the development of new therapies for motor neuron disease, but deriving skeletal...
Study Suggests Respiratory Pacemaker Reduces ALS Survival
August 21, 2015
Since 2011, a pacemaker that controls diaphragm contractions has been available to help people with ALS breathe. A humanitarian exemption from the FDA allows...
New C9ORF72 Antibodies Find Isoforms in Different Cellular Locations
August 14, 2015
The C9ORF72 gene has been linked to both amyotrophic lateral sclerosis and frontotemporal dementia. Researchers trying to understand the function of the...
Does New Role for ALS-Linked Protein Help Explain Neurodegeneration?
August 8, 2015
As the cell processes gene transcripts into mature mRNAs, just a few specific nucleotides mark sites where exons are spliced in, and introns spliced out. What if, by chance,...




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