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We Value your Feedback!
February 27, 2015
Your feedback is important to us as we work to improve and expand the ALS Forum. The portal was developed as a web-based resource to attract more researchers to study ALS, and to provide both new and veteran ALS researchers with valuable information and tools to help accelerate ALS research. Your input will help us improve the site and assess its impact...

NAD+ Depletion Underlies Neuronal Death Triggered by Misfolded Prion Proteins
February 24, 2015
Misfolded proteins, which accumulate in neurodegenerative diseases such as ALS, Alzheimer’s and Parkinson’s disease, can trigger misfolding and aggregation of their non-mutant protein counterparts in a prion-like manner...

Awareness Has Arrived: Two Oscars for Movies About Neurodegenerative Disease
February 23, 2015

Last night at the Oscar ceremony, two of the coveted statuettes went to depictions of Alzheimer’s disease and amyotrophic lateral sclerosis. As expected, Julianne Moore won the award for Best Actress in a Leading Role for her portrayal of a woman with early onset Alzheimer’s in “

TANK-Binding Kinase 1 Rumbles in as New ALS Gene
February 20, 2015

An army of geneticists scouted for disease genes in the DNA of people with amyotrophic lateral sclerosis. They found a TANK. TANK-binding kinase 1, to be precise, or TBK1 to its allies. The gene, which mobilizes in autophagy and neuroinflammation,...

Europe Leads the Way Toward Standardization and Brain Bank Networks
February 18, 2015

This is Part 2 of a 2-part series

No one in the field of neurodegeneration research disputes the central importance of brain banks, but that does not mean there are no complaints about them. For one, the quality of banked tissue varies widely...

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