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Fishing for the ‘Missing Heritability’ of ALS
July 22, 2014

Scientists have not nearly plumbed the depths of genetic associations with sporadic amyotrophic lateral sclerosis, according to a new analysis in the July 14 JAMA Neurology online. First author Margaux Keller and colleagues at the National Institute on Aging in Bethesda, Maryland, measured...

Neurons and Cancer Cells Share Survival Tactics
July 18, 2014

How do neurons endure for the life of an organism? In the July 15 Science Signaling, researchers led by Mohanish Deshmukh at the University of North Carolina, Chapel Hill, report that these cells can resist insults that cause other cells to commit suicide. The researchers identified parkin-like...

Heart-Healthy Fatty Acids May Stave Off ALS
July 18, 2014

The benefit to cardiovascular health offers one reason to chow down on foods loaded with omega-3 fatty acids. A paper in the July 14 JAMA Neurology online adds another: The same chemicals pare down a person’s risk of developing amyotrophic lateral sclerosis. Researchers at the Harvard...

Pocketful of Posies: Does a Supersized Vesicle Bouquet Promote ALS?
July 14, 2014

A bouquet of protein strands, capped with presynaptic vesicles, offers up a clue to neurotransmission defects that might occur early in amyotrophic lateral sclerosis. This is the essence of a paper in the July 10 Cell Reports by senior author Patrik Verstreken and colleagues at the VIB...

UK ‘Whole Genome Sequencing Project’ to Sequence 1,500 ALS Genomes
July 10, 2014
The UK Whole Genome Sequencing Project is an exciting new initiative to sequence 1500 genomes from ALS patients just announced by the UK Motor Neurone Disease (MND) Association . The goal of the project is to identify previously unknown, rare genetic variants that contribute to the sporadic forms of the disease...

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