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ALS Model Mice Roar Back When Human Transgene Silenced
November 20, 2015
Neurodegeneration is usually pretty permanent—but TDP-43 mice are making a comeback. One line of mice deteriorated during six weeks when a  TDP-43 transgene was...
Stressed Out: RNA-binding Protein Inhabits Granules in ALS, FTD
November 18, 2015
Panning the cerebrospinal fluid of people with amyotrophic lateral sclerosis, researchers discovered a new pathological marker in RNA-binding motif 45 (RBM45). In diseased...
Listen Up, Gene Silencing Strikes a Chord at RNA Meeting
November 14, 2015
Scientists are taking the offensive against neurodegeneration, with tiny nucleic acids as one of their favored weapons. RNA Metabolism in Neurodegenerative Disease, an SfN...
New Findings Highlight Mechanism for Selective Neurodegeneration in CMT
November 11, 2015
Charcot-Marie-Tooth (CMT) disease, also known as hereditary motor and sensory neuropathy, is one of the most common inherited neurological disorders, affecting approximately 1...
Vascular Defects May Contribute to Spinal Muscular Atrophy
November 10, 2015
Spinal muscular atrophy is a fatal childhood motor neuron disease, which affects approximately 1 in 6000 infants. According to a report in the Oct 27 Annals of...

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